Association of Ornithine Transcarbamylase Gene Polymorphisms With Hypertension and Coronary Artery Vasomotion

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Association of ornithine transcarbamylase gene polymorphisms with hypertension and coronary artery vasomotion.

BACKGROUND Previous studies have suggested that the activity of enzymes involved in the urea cycle may modulate nitric oxide (NO) production, arterial vasomotion, and hypertension. Our aim was to determine whether hypertension and coronary vasomotion could be associated with polymorphisms within the ornithine transcarbamylase (OTC) gene, located on chromosome X and coding for a key-enzyme of th...

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ژورنال

عنوان ژورنال: American Journal of Hypertension

سال: 2009

ISSN: 1941-7225,0895-7061

DOI: 10.1038/ajh.2009.110